Mixed Mode C8 SCX SPE Cartridges

Function group: C8/Sulfonicacid group;
Retention Mechanism:
reversed-phase/cation-exchange selectivity;

Description of C8/SCX mixed mode SPE cartridge

Mixed Mode C8 SCX SPE Cartridge is a kind of mixed-mode sorbent for extracting basic compounds, normally it is used for drugs and metabolites from physiological fluids. The functional group of C8/SCX is composed of the octyl group and the sulfonic acid group bonded in proportion, and has a dual retention effect: the octyl group provides a medium hydrophobic effect, and the sulfonic acid group provides a strong cation exchange effect. For samples that are difficult to elute due to excessive adsorption of C18 and C8 and excessive retention of SCX, C8/SCX mixed mode SPE cartridge can be used.


Great PE made frits to avoid pollution.
PH ranges widely.
All kinds of imported sorbents are available.
Personalized print logo and package for you to choose from.
All series of cartridge volumes and styles to choose from.


Function group: C8/SCX
Particle size: 40-75μm/230-400 mesh
pore size: 70Å

Applications of Mixed Mode C8 SCX SPE Cartridge

Performs best in the extraction of alkali compounds.
Suitable for all small molecule compounds (alkaline, neutral, acidic, and amphoteric compounds) from biological media extraction such as blood samples, urine samples, and tissues.
Mixed mode C8 SCX SPE cartridge is used for further analysis such as GC-MS or LC-MS/MS.
Applied to the research of pre-clinical drug metabolism, and clinical drug metabolism.

It is well known that SPE cartridges are widely used in many fields such as drug metabolism and kinetics, drug analysis, biological detection, drug, and stimulant testing, food safety analysis, environmental analysis, etc. SPE cartridges have various types according to their different bases, but the C8/SCX mixed mode SPE cartridge is the most widely used in all solid phase extraction products. Like C18 in liquid chromatography, the C8/SCX mixed mode SPE cartridge dominates.

Extracting Basic Drugs in Biological Fluids

Technical Data

SpecificationMaximum Sample LoadVolumeMinimum Elution Volume

Ordering Information

Item   No. SpecificationPackage (pcs/pk)
SLSPE301C8SCXC8/SCX, 30mg/1mL100
SLSPE1001C8SCXC8/SCX, 100mg/1mL100
SLSPE2003C8SCXC8/SCX, 200mg/3mL50
SLSPE5003C8SCXC8/SCX, 500mg/3mL50
SLSPE2006C8SCXC8/SCX, 200mg/6mL30
SLSPE5006C8SCXC8/SCX, 500mg/6mL30
SLSPE1K12C8SCXC8/SCX, 1g/12mL20
SLSPE2K12C8SCXC8/SCX, 2g/12mL20
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